Male hypogonadism, or low testosterone, is a disorder where your testicles do not produce enough of the hormone (the male sex hormone). The gonads (sex organs) of those born as males are the testicles (AMAB). Your testicles mainly produce testosterone, thanks to Leydig cells. There can be several low testosterone causes in men.
At various ages, low testosterone produces multiple symptoms. As individuals’ AMAB age, their levels of testosterone gradually decrease. This applies to transgender people who aren’t receiving feminizing hormone therapy, cisgender men, non-binary people, and AMAB. There are different ways of treating low testosterone. One can take medicines such as Tadalafil, Cenforce, etc that can help treat problems of erectile dysfunction.
What Does Having Low Testosterone Mean?
For adults, a low blood testosterone level is less than 300 nanograms per deciliter (ng/dL) to the American Urology Association (AUA).
Some scientists and medical professionals disagree with this, believing that levels under 250 ng/dL are minimal. When diagnosing low testosterone cause in men, professionals also analyze the symptoms.
Why Do Testosterone Level Fall?
Several factors could cause low testosterone. Men can have one of two forms of hypogonadism:
- First-order hypogonadism (testicular disorder).
- Secondary hypogonadism (dysfunction of the hypothalamus and pituitary).
There are two categories for the causes of primary and secondary hypogonadism: congenital (present at birth) and acquired (developed later in childhood or adulthood).
Main Male Hypogonadism causes?
You have primary hypogonadism when there is a problem with your testicles that prevents them from producing normal testosterone levels. Let us take a look at some of the low testosterone causes.
Hypogonadotropic hypogonadism is another term for primary hypogonadism. In this type, the pituitary gland increases the production of the gonadotropins luteinizing hormone (LH) and follicle-stimulating hormone (FSH) in response to low testosterone levels.
Usually, the high amounts of these chemicals would instruct your testicles to make more sperm and testosterone. However, your testicles won’t respond to the higher quantities of gonadotropins if they are injured (most frequently caused by past chemotherapy) or absent. Your testicles produce either too little or no testosterone and sperm as a result.
Gonadotropin levels and testosterone levels can occasionally be normal in primary hypogonadism. Even if your testosterone levels are normal, your doctor will be able to tell you if you require medication.
Primary hypogonadism can result from several congenital diseases that affect your testicles, including:
- At birth, there were no testicles (anorchia).
- Undescended testicles (cryptorchidism).
- The absence of Leydig cells (underdevelopment of Leydig cells in your testicles).
- Insufficiency of Klinefelter (a genetic condition in which people AMAB are born with an extra X chromosome: XXY instead of XY).
- Syndrome Noonan (a rare genetic condition that can cause delayed puberty, undescended testicles, or infertility).
- Dystonia myotonic (part of a group of inherited disorders called muscular dystrophies).
Causes of Male Secondary Hypogonadism
Secondary hypogonadism is when your hypothalamus and pituitary gland is not functioning correctly. Low luteinizing hormone (LH) and follicle-stimulating hormone levels produce this condition, known as hypogonadotropic hypogonadism (FSH).
Reduced testosterone and sperm production result from those low levels. There can be several side effects of low testosterone. It can often lead to problems like erectile dysfunction. You may find it difficult to last longer in bed. There can be several kinds of testosterone deficiency syndrome.
The following congenital disorders can result in secondary hypogonadism:
- Isolated hypogonadotropic hypogonadism (a condition that causes low levels of gonadotropin-releasing hormone from birth).
- An uncommon genetic disorder called Kallmann syndrome prevents the growth of nerve cells in your hypothalamus that make gonadotropins-releasing hormones. It could also result in a loss of smell.
- Prader-Willi condition (a rare genetic multisystem disorder than can cause hypothalamus dysfunction).
Low Testosterone Treatment
There are several ways to treat low testosterone. This includes injections, medicines, skin gels, oral medications such as Kamagra, Cenforce, etc, and a lot more.
Low testosterone causes cannot be fixed in a single step. However, for many AMAB who are experiencing low testosterone, regular hormone replacement medication helps to boost sex desire, reduce depressive symptoms, and increase energy levels. Additionally, treating testosterone may increase bone density and muscle mass. Medication for low testosterone is mandatory.
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